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This dose may need to be increased after one or two weeks to up to 45 mg once a day if better blood glucose (sugar) control is needed. Treatment with Actos should be reviewed after three to six months, and discontinued in patients who are not deriving sufficient benefit.
At subsequent reviews prescribers should confirm that benefits to patients are maintained.
It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing authorisation and its recommendations on the conditions of use for Actos.
The recommended starting dose of Actos is 15 or 30 mg once a day.